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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Cardiothorac Vasc Anesth. 2011 May 25;25(6):931–936. doi: 10.1053/j.jvca.2011.03.008

Table 3. Pharmacokinetic Parameters of the Final Model and the 95% Confidence Interval Using the Bootstrap Resampling Procedure.

Original Data Set 1000 Bootstrap Replicates
Parameter Estimate % CV Estimate 95% Confidence Interval
V1 (l/kg) 0.062 12% 0.056 0.031 – 0.64
V2 (l) 187 24% 187 137 – 207
CL1 (l/kg/min) 0.0042 26% 0.0042 0.0038 – 0.0045
CL2 (l/min) 8.92 73% 6.76 3.6 – 65.1
*

V1 = volume of the central compartment; V2 = volume of the peripheral compartment CL1 = elimination clearance; CL2 = intercompartmental clearance; CV = coefficient of variation.