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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Arthritis Rheum. 2011 Nov;63(11):3448–3457. doi: 10.1002/art.30530

Figure 2.

Figure 2

TRAIL expression is localized to perifascicular atrophic and regenerating areas of DM muscle. Serial sections from DM muscle biopsies were stained with antibodies against TRAIL. (A) (B) TRAIL is colocalized with developmental myosin heavy chain (dMHC) in perifascicular region. (C) Control and myositis human muscle homogenates were probed with antibodies against Beclin (top) or LC3 (middle) and Vinculin (bottom) expected sizes marked with arrows. (D) Differentially expressed autophagy pathway genes from myositis and DMD patients were compared to normal human muscle (NHM). All gene differences reported were statistically significant after multiple testing corrections. Data expressed as -fold change.