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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Anesthesiology. 2011 Nov;115(5):992–1002. doi: 10.1097/ALN.0b013e3182303a63

Figure 2. Anesthesia promotes autophagic activity, as shown in subicular pyramidal neurons of 21-day-old rats.

Figure 2

A) In experimental pyramidal neurons, numerous lysosomes (double asterisks) and autophagic vacuoles (arrowheads) were dispersed throughout the cytoplasm. B) Autophagosomes, double-layered membrane structures, were frequently noted in experimental neurons where parts of cannibalized mitochondria could be detected (single asterisk).