Figure 3.

Percentage of over-estimation productivity for different perturbation region. The percentage of over-estimation productivity for different scale perturbation. The perturbation region for each enzyme is selected as R-fold below and above its basal value, i.e., $\left[{\gamma }_{e_i}^{LB},{\gamma }_{e_i}^{UB}\right]=\left[1∕R,R\right]$.