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A gene expression signature of p63 silencing discriminates between lymph nodes and tonsils. In GEO series GSE2665, openSESAME identified that samples of lymph nodes and tonsillar tissue are positively and negatively associated with the p63-silencing signature, respectively, suggesting that p63 is important for maintenance of the stratified squamous epithelium that is present in tonsils but is absent from lymph nodes.
