Table 2.
Characteristics of Colorectal Cancer Cases in the NIH-AARP Diet and Health Study, 1995–2005/2006a
| Variable | Quartile of Socioeconomic Deprivation |
P Valueb | |||
| 1 (Least Deprived) (n = 1,922) | 2 (n = 1,781) | 3 (n = 1,719) | 4 (Most Deprived) (n = 1,594) | ||
| Demographic characteristics | |||||
| Age, years | 0.102 | ||||
| <65 | 534 (27.8) | 464 (26.1) | 419 (24.4) | 424 (26.6) | |
| 65–69 | 630 (32.8) | 646 (36.3) | 590 (34.3) | 554 (34.8) | |
| ≥70 | 758 (39.4) | 671 (37.7) | 710 (41.3) | 616 (38.6) | |
| Sex | <0.001 | ||||
| Female | 496 (25.8) | 524 (29.4) | 558 (32.5) | 620 (38.9) | |
| Male | 1,426 (74.2) | 1,257 (70.6) | 1,161 (67.5) | 974 (61.1) | |
| Race/ethnicity | <0.001 | ||||
| Non-Hispanic white | 1,860 (96.8) | 1,703 (95.6) | 1,611 (93.7) | 1,275 (80.0) | |
| Other | 62 (3.2) | 78 (4.4) | 108 (6.3) | 319 (20.0) | |
| Education | <0.001 | ||||
| Less than high school graduation | 434 (22.6) | 529 (29.7) | 566 (32.9) | 547 (34.3) | |
| High school/some college | 602 (31.3) | 616 (34.6) | 601 (35.0) | 532 (33.4) | |
| College graduation or more | 842 (43.8) | 589 (33.1) | 489 (28.5) | 443 (27.8) | |
| Missing data | 44 (2.3) | 47 (2.6) | 63 (3.7) | 72 (4.5) | |
| Marital status | <0.001 | ||||
| Married/living as married | 1,541 (80.2) | 1,330 (74.7) | 1,170 (68.1) | 967 (60.7) | |
| Never married/widowed/separate/divorced | 366 (19.0) | 438 (24.6) | 534 (31.1) | 610 (38.3) | |
| Missing data | 15 (0.8) | 13 (0.7) | 15 (0.9) | 17 (1.1) | |
| Cancer characteristics | |||||
| CRC site | 0.965 | ||||
| Proximal | 755 (39.3) | 704 (39.5) | 652 (37.9) | 629 (39.5) | |
| Distal | 583 (30.3) | 529 (29.7) | 528 (30.7) | 459 (28.8) | |
| Colon (unspecified) | 62 (3.2) | 58 (3.3) | 61 (3.6) | 51 (3.2) | |
| Rectum | 522 (27.2) | 490 (27.5) | 478 (27.8) | 455 (28.5) | |
| CRC stage | 0.001 | ||||
| In situ/local | 787 (41.0) | 681 (38.2) | 664 (38.6) | 646 (40.5) | |
| Regional | 578 (30.1) | 510 (28.6) | 492 (28.6) | 485 (30.4) | |
| Distant | 212 (11.0) | 214 (12.0) | 219 (12.7) | 219 (13.7) | |
| Unstaged/missing data | 345 (18.0) | 376 (21.1) | 344 (20.0) | 244 (15.3) | |
| CRC grade | 0.064 | ||||
| Well-differentiated | 225 (11.7) | 214 (12.0) | 177 (10.3) | 161 (10.1) | |
| Moderately differentiated | 1,019 (53.0) | 963 (54.1) | 942 (54.8) | 914 (57.3) | |
| Poorly differentiated | 280 (14.6) | 240 (13.5) | 254 (14.8) | 244 (15.3) | |
| Missing data | 398 (20.7) | 364 (20.4) | 346 (20.1) | 275 (17.3) | |
| Health conditions | |||||
| Body mass indexc | <0.001 | ||||
| <25 | 626 (32.6) | 539 (30.3) | 552 (32.1) | 505 (31.7) | |
| 25–<30 | 860 (44.8) | 809 (45.4) | 773 (45.0) | 655 (41.1) | |
| 30–<35 | 336 (17.5) | 309 (17.4) | 300 (17.5) | 285 (17.9) | |
| ≥35 | 100 (5.2) | 124 (7.0) | 94 (5.5) | 149 (9.4) | |
| Comorbidity | <0.001 | ||||
| No | 1,483 (77.2) | 1,298 (72.9) | 1,270 (73.9) | 1,129 (70.8) | |
| Yes | 439 (22.8) | 483 (27.1) | 449 (26.1) | 465 (29.2) | |
| Health-related behaviors | |||||
| Frequency of physical activity | <0.001 | ||||
| Never/rare | 339 (17.6) | 367 (20.6) | 383 (22.3) | 395 (24.8) | |
| 1–3 times/month | 266 (13.8) | 225 (12.6) | 223 (13.0) | 211 (13.2) | |
| 1–2 times/week | 409 (21.3) | 385 (21.6) | 381 (22.2) | 320 (20.1) | |
| 3–4 times/week | 536 (27.9) | 464 (26.1) | 406 (23.6) | 363 (22.8) | |
| ≥5 times/week | 354 (18.4) | 324 (18.2) | 301 (17.5) | 271 (17.0) | |
| Missing data | 18 (0.9) | 16 (0.9) | 25 (1.5) | 34 (2.1) | |
| Smoking | <0.001 | ||||
| Never smoker | 589 (30.7) | 483 (27.1) | 466 (27.1) | 471 (29.6) | |
| Former smoker | |||||
| ≤20 cigarettes/day | 522 (27.2) | 502 (28.2) | 461 (26.8) | 438 (27.5) | |
| >20 cigarettes/day | 538 (28.0) | 529 (29.7) | 485 (28.2) | 388 (24.3) | |
| Current smoker | |||||
| ≤20 cigarettes/day | 116 (6.0) | 129 (7.2) | 162 (9.4) | 152 (9.5) | |
| >20 cigarettes/day | 62 (3.2) | 72 (4.0) | 71 (4.1) | 71 (4.5) | |
| Missing data | 95 (4.9) | 66 (3.7) | 74 (4.3) | 74 (4.6) | |
| Heavy alcohol consumption (≥15 g/day) | 0.818 | ||||
| No | 1,903 (99.0) | 1,759 (98.8) | 1,698 (98.8) | 1,573 (98.7) | |
| Yes | 19 (1.0) | 22 (1.2) | 21 (1.2) | 21 (1.3) | |
| Mediterranean dietary score | 0.027 | ||||
| 0–3 | 702 (36.5) | 702 (39.4) | 696 (40.5) | 605 (38.0) | |
| 4–5 | 774 (40.3) | 693 (38.9) | 687 (40.0) | 674 (42.3) | |
| 6–9 | 446 (23.2) | 386 (21.7) | 336 (19.6) | 315 (19.8) | |
| Self-rated health | <0.001 | ||||
| Very good/excellent | 1,015 (52.8) | 833 (46.8) | 773 (45.0) | 662 (41.5) | |
| Good | 678 (35.3) | 671 (37.7) | 646 (37.6) | 608 (38.1) | |
| Fair/poor | 194 (10.1) | 251 (14.1) | 282 (16.4) | 294 (18.4) | |
| Missing data | 35 (1.8) | 26 (1.5) | 18 (1.1) | 30 (1.9) | |
Abbreviations: CRC, colorectal cancer; NIH, National Institutes of Health.
a
Eight subjects with missing data on socioeconomic deprivation were excluded from the model.
b
χ2 test.
c
Weight (kg)/height (m)2.