Table 3.
Relationships to Plaque Characteristics (Pearson and Spearman Correlation Coefficient) in All Participants
| Characteristic | Percentage of noncalcified plaque | Natural log (Ca score +1) |
| Traditional risk factors | ||
| Age | ρ = −0.12, P =.32 | r = 0.36, P < .0001 |
| Framingham risk score | ρ = −0.21, P =.08 | r = 0.37, P < .0001 |
| Systolic blood pressure | ρ = 0.04, P =.73 | r = 0.12, P =.15 |
| Diastolic blood pressure | ρ = 0.19, P =.10 | r = 0.12, P =.15 |
| Total cholesterol | ρ =−0.24, P =.04 | r = 0.32, P < .0001 |
| Low-density lipoprotein cholesterol | ρ =−0.18, P =.14 | r = 0.25, P =.003 |
| High-density lipoprotein cholesterol | ρ =−0.03, P =.78 | r = −0.10, P =.25 |
| Triglycerides | ρ =−0.20, P =.09 | r = 0.33, p < .0001 |
| Monocyte/macrophage activation markers | ||
| sCD163 | ρ =0.23, P =.047 | r = −0.04, P =.62 |
| Lipopolysaccharide | ρ =0.05, P =.68 | r = 0.06, P =.47 |
| sCD14 | ρ =0.26, P =.03 | r = −0.07, P =.39 |
| Osteopontin | ρ =−0.01, P =.94 | r = −0.06, P =.47 |
| Markers of generalized inflammation, coagulation, and cytomegalovirus | ||
| hs interleukin-6 | ρ =0.17, P =.17 | r = 0.03, P =.77 |
| C-reactive protein | ρ =0.14, P =.22 | r = −0.07, P =.37 |
| D-dimer | ρ =−0.12, P =.29 | r = −0.06, P =.46 |
| Cytomegalovirus immunoglobulin G titers | ρ =−0.10, P =.44 | r = 0.16, P =.09 |