Figure 2.

Detection of mouse-adapted Zaire ebolavirus (MA-ZEBOV) genome equivalents in mice immunized with recombinant vesicular stomatitis virus (rVSV) vectors expressing different Ebola virus glycoproteins (EBOV-GPs). Mice (n = 5) were vaccinated with a single dose of rVSV vectors and challenged 3 weeks later with 1000 median lethal dose (LD₅₀) of MA-ZEBOV. Animals were killed 5 days postchallenge, blood samples were collected, and RNA was extracted. Quantitative real-time reverse-transcriptase polymerase chain reaction (RT-PCR) data are shown as genome equivalents per 1 mL blood. Error bars represent the standard error of the mean.