Table 3.
Significant associations with IR, stratified by CKD among Health ABC participants
| Participant characteristics | Overall (with eGFR), odds ratio (95% CI)a | Overall (with CKD), odds ratio (95% CI) | Without CKD, odds ratio (95% CI)a | With CKD, odds ratio (95% CI)a |
| Age (per 1 year) | 1.00 (0.96–1.04) | 1.00 (0.96–1.04) | 1.00 (0.96–1.05) | 1.02 (0.93–1.13) |
| Race (black) | 1.90 (1.41–2.56) | 2.05 (1.54–2.74) | 1.99 (1.44–2.74) | 2.63 (1.32–5.24) |
| Sex (women) | 1.10 (0.80–1.52) | 1.00 (0.73–1.36) | 1.16 (0.81–1.66) | 0.70 (0.34–1.43) |
| CKD | NA | 1.57 (1.15–2.74) | NA | NA |
| eGFR (per 10 mL/min/1.73m2 | 0.92 (0.87–0.98) | NA | NA | NA |
| Current smoker | 0.62 (0.39–0.98) | 0.62 (0.39–0.99) | 0.51 (0.29–0.88) | NS |
| Log triglycerides per SD | 1.59 (1.39–1.82) | 1.60 (1.40–1.83) | 1.49 (1.27–1.75) | 1.94 (1.41–2.69) |
| HDL per SD | NS | NS | 0.82 (0.68–0.99) | NS |
| Log adiponectin per SD | 0.58 (0.51–0.67) | 0.59 (0.52–0.68) | 0.57 (0.49–0.67) | |
| Log IL6 per SD | NS | NS | NS | 1.47 (1.07–1.97) |
| Log visceral fat per SD | 2.05 (1.71–2.46) | 2.15 (1.81–2.56) | 2.06 (1.69–2.50) | 2.47 (1.64–3.72) |
| Log subcutaneous fat per SD | 1.62 (1.30–2.00) | 1.80 (1.49–2.17) | 1.82 (1.46–2.25) | 2.01 (1.31–3.08) |
| Log muscle fat per SD | 1.19 (1.00–1.42) | NS | NS | NS |
a
Age, race, sex forced into model; available for model systolic BP, log(TNF), log(adiponectin), log(CRP), log(IL-6), log (intermuscular fat), log(visceral fat), log(abdominal subcutaneous fat) and CKD or eGFR; NA: not applicable, NS: not significant.