Figure 3.

Hypothetical Models of Repression by JAZ Proteins.

(A) In the absence of JA-Ile, JAZ proteins bind and inhibit MYC2 DNA binding activity.

(B) to (D) In the absence of JA-Ile, the corepressor TPL is recruited to the MYC2 complex through EAR motif–containing proteins.

(B) The adaptor protein NINJA links TPL to the MYC2-bound JAZ proteins.

(C) and (D) Some JAZ proteins (such as JAZ5 and JAZ6) contain endogenous EAR motifs and might link TPL to MYC2 by direct binding (C) or through heterodimerization with other JAZ proteins (D).