Figure 3.

Strand separation of DNA under tension from simulation. (a) Simulated system of dsDNA in a bath of solvent and ions, as described in ‘Methods’ section. (b) Snapshots of DNA during a steered molecular dynamics simulation (simulation F1, see Supplementary Table S1). The atoms, at the 5′-end of the DNA strands, subject to constraint force (at bottom) and stretching force (at top), are highlighted in green. A movie (Supplementary Movie S1) showing the strand separation of DNA is provided in Supplementary Data.