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Incision kinetics of the internally labeled 135-mer modified duplexes in HeLa cell extracts. The incision efficiencies were normalized in each of the four independent experiments to the value obtained with the C8-dG-PhIP full duplex (relative value of 100) at the 30 min incubation time point. The averages and standard deviations shown were obtained from these normalized values. Note that the cis-B[a]P-dG deletion duplex is not incised.
