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. 2011 Jul 23;39(20):8677–8688. doi: 10.1093/nar/gkr593

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© The Author(s) 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Modular structure of the network. Adjacency matrix of the network before (a) and after (b) the hierarchical clustering procedure used to identify communities. Each dot represents a connection among two genes, that is a matrix entry, whose MI is greater than the significance threshold. (a) Genes are sorted according to their chromosomal location. Numbers on the x and y axes indicate chromosomes. (b) Genes are sorted according the community they belong to. Square dimensions are proportional to the number of genes in each community. The inset shows an enlargement of an area of the adjacency matrix where single dots are visible.