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Effect of GagNC mutations on splicing
| wt | R7R10K11S | K14D | H23C | ΔZF1 | H44C | ΔZF2 | P31L | K59L |
|---|---|---|---|---|---|---|---|---|
| MS/FL (%) | ||||||||
| 100 | 81 ± 28 | 83 ± 34 | 112 ± 7 | 94 ± 25 | 108 ± 4 | 99 ± 21 | 76 ± 21 | 129 ± 28 |
The ratio of MS to FL RNAs were normalized to ratio determined in cells transfected with wt HIV-1. The values represent mean ± SD of at least three independent experiments.
