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. Author manuscript; available in PMC: 2011 Oct 28.
Published in final edited form as: Tetrahedron. 2008 Jul 14;64(29):6870–6875. doi: 10.1016/j.tet.2008.03.071

Table 2.

Scope of Enyne Cycloisomerizationa

entry enyne product yield (%)b,c
1 graphic file with name nihms56365t1.jpg
1 R = Me 2 90
3 R = Et 4 92
5 R = nPr 6 97
7 R = iPr 8 99
2 graphic file with name nihms56365t2.jpg
9
10 82
a

Reaction Conditions: 5 mol% Ni(COD)2, 10 mol% IDTB, 0.1M 1, 60 °C, 1h.

b

Isolated yield, average of two runs.

c

>95:5 E:Z based on 1H NMR analysis of crude reaction mixture.