Table 2.
Univariate and multivariate analyses of PFS
| Univariate Analysis | |||
|---|---|---|---|
| N | HR (95% CI) | p | |
| Age (years) | 60 | 1.01 (0.98-1.04) | 0.63 |
| PS 0 | 14 | 1.03 (0.52-2.04) | 0.94 |
| PS 1-2 | 46 | 1 Ref. | |
| Male | 36 | 1.48 (0.81-2.70) | 0.21 |
| Female | 24 | 1 Ref. | |
| Adenocarcinoma | 39 | 1 Ref. | 0.05 |
| Non-adenocarcinoma | 21 | 1.84 (1.01-3.33) | |
| Smoker | 22 | 1.26 (0.64-2.49) | 0.51 |
| Non- smoker | 27 | 1 Ref. | |
| EGFR mutated | 9 | 1 Ref. | 0.32 |
| EGFR wild-type | 41 | 1.55 (0.65-3.73) | |
| K-ras mutated | 10 | 1.21 (0.58-2.53) | 0.62 |
| K-ras wild-type | 46 | 1 Ref. | |
| Low BRCA1&AEG1 expression | 18 | 1 Ref. | |
| High BRCA1&AEG1 expression | 17 | 3.08 (1.33-7.15) | 0.009 |
| Other combinations of BRCA1&AEG1 expression | 25 | 1.70 (0.82-3.53) | 0.15 |
| Multivariate Analysis | |||
| Low BRCA1&AEG1 expression | 18 | 1 Ref. | |
| High BRCA1&AEG1 expression | 17 | 3.11 (1.30-7.47) | 0.01 |
| Other combinations of BRCA1&AEG1 expression | 25 | 2.18 (0.99-4.78) | 0.05 |
| Adenocarcinoma | 39 | 1 Ref. | |
| Non-adenocarcinoma | 21 | 1.52 (0.79-2.91) | 0.21 |
| Male | 36 | 1.60 (0.84-3.07) | 0.16 |
| Female | 24 | 1 Ref. | |