Figure 3. Extracellular calcium influx across the plasma membrane channels mediates the calcium response upon mechanical stimulation.
The bar graphs represent the percentage of cells with global, local, or none responses under different treatment as indicated, with the error bars representing the respective standard deviations. EGTA (extracellular calcium chelator): p = 1×10−10, Gadolinium (Gd3+, stretch-activated calcium channel blocker): p = 0.007, Streptomycin (Strep, stretch-activated calcium channel blocker): p = 0.02. The statistical difference from the control group is determined by p<0.05. All results were significantly different from control.