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. 2011 Oct 28;6(10):e26988. doi: 10.1371/journal.pone.0026988

Figure 4. NIH microbiota induced expression of IL-22 and reg3β.

Figure 4

Relative expression in the ileum (a) for IL22-, Reg3γ-, and Reg3β-specific mRNA in NIH Swiss (NIH), C3H/HeJ transplanted with NIH microbiota (HeJ-NIH), C3H/HeJ transplanted with HeJ-Naïve (HeJ-HeJ) and C3H/HeJ (HeJ-Naïve) mice relative to HeJ-HeJ mice. (b) Immunostaining for Reg3β in ileal sections shows abundant peptide in ilea of NIH and HeJ-NIH mice, but not in HeJ-HeJ and HeJ-Naïve mice. The scale bar is equal to 50 µm. Data represents mean±SEM. (c) IL-22 and Reg3β expression in NIH mice transplanted with HeJ microbiota (NIH-HeJ) or NIH microbiota (NIH-NIH). All figures representative of two independents experiments with n = 4.