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. 2011 Nov;66(11):1923–1928. doi: 10.1590/S1807-59322011001100012

Table 1.

Studies characteristics.

Results (POAF)
Study N Study design Control Inclusion criteria Exclusion criteria PUFA Control
Calo 160 Open-label, prospective, randomized, controlled trial with parallel groups; not blinded No PUFA Age >18, NSR, stable hemodynamic conditions before surgery Concomitant valvular surgery, a prior history of any SVT, the current use of an AAD other than BB, CCB, or digitalis 15.2% 33.3%
Heidt 102 Prospective, randomized double-blinded trial IV saturated free fatty acids Age >18, NSR, stable hemodynamic conditions before surgery, no angina at rest Concomitant valvular surgery, a prior history of any SVT, the current use of an AAD other than BB or CCB 17.3% 30.6%
Heidarsdottir 168 Prospective, randomized, double-blinded, placebo-controlled trial Placebo All of the consecutive patients scheduled for elective or open heart surgery Age <40, prior history of any SVT, the current use of amiodarone or sotalol, an emergent operation 54.2% 54.1%
Saravanan 103 Prospective, randomized, double-blinded, placebo-controlled trial Placebo Age >18, scheduled to undergo elective isolated CABG A prior history of any atrial arrhythmia, the current use of a class-1 or class-3 AAD, fish oil use within 3 mos prior to surgery 56% 43%

AAD, antiarrhythmic drugs; BB, beta-blockers; CABG, coronary artery bypass grafting; CCB, calcium channel blockers; IV, intravenous; NSR, normal sinus rhythm; POAF, postoperative atrial fibrillation; PUFA, polyunsaturated fatty acid; SVT, supraventricular tachycardia.