Table 3.
The PUFA type and dose, the definition of AF, and the rhythm surveillance method.
Study | Type/dose of PUFA | Definition of AF | Rhythm surveillance |
Calo | Daily doses of 850–882 mg EPA and DHA in an average ratio of 1:2 EPA:DHA, initiated at least 5 days before surgery and continued until hospital discharge | Any episode lasting more than 5 min or requiring intervention | Continuous rhythm monitoring for the first 4–5 days, followed by daily ECG until hospital discharge |
Heidt | Infusion pump (100 mg soya oil/kg body weight/day) started at least 12 hours before surgery and continued until transfer to the ward | Any episode lasting more than 15 min | Monitoring or 12-lead ECG during the ICU period |
Heidarsdottir | Two capsules twice daily for a daily dose of 1240 mg EPA, initiated 5–7 days before surgery and continued until hospital discharge or a maximum of 2 weeks after surgery | Any episode lasting more than 5 min | Continuous ECG monitoring during hospitalization |
Saravanan | Daily doses of 2 mg of a commercially available n-3 PUFA preparation, providing 85–88% EPA+DHA as ethyl esters in a ratio of 1∶2∶1 and initiated at least 5 days before CABG and continued until the day of discharge | Any episode lasting more than 30 sec | Heart rhythm monitoring (Holter) from the immediate post-op period to 5 days after surgery; if the patient was hospitalized for longer than 5 days, ECG was performed daily |
CABG, coronary artery bypass grafting; DHA, docosahexaenoic acid; ECG, electrocardiograph; EPA, eicosapentaenoic acid; ICU, intensive care unit; PUFA, polyunsaturated fatty acid.