Table 1.
Baseline characteristics of study population
| Total population | Women | Men | p-value | |
|---|---|---|---|---|
| (n = 951) | (n = 234) | (n = 717) | ||
| Clinical parameters | ||||
| Age (years) | 64 ± 10.6 | 67 ± 9.9 | 63 ± 10.6 | <0.001 |
| BMI (kg/m2) | 27.3 ± 3.9 | 27.2 ± 4.7 | 27.3 ± 3.6 | 0.607 |
| Current smoker | 102 (10.7%) | 24 (10.3%) | 78 (10.9%) | 0.785 |
| Diabetes mellitus | 175 (18.4%) | 53 (22.6%) | 122 (17.0%) | 0.053 |
| Hypertension | 737 (77.5%) | 186 (79.5%) | 551 (76.8%) | 0.401 |
| Hypercholesterolaemia | 769 (80.9%) | 189 (80.8%) | 580 (81.0%) | 0.936 |
| Familial history | 580 (61.4%) | 171 (74.0%) | 409 (57.4%) | <0.001 |
| Prior myocardial infarction | 432 (45.4%) | 94 (40.2%) | 338 (47.1%) | 0.063 |
| Impaired ejection fraction | 133 (14.0%) | 35 (15.0%) | 98 (13.7%) | 0.622 |
| Renal failure | 93 (9.8%) | 22 (9.4%) | 71 (9.9%) | 0.809 |
| Medication | ||||
| Loading dose clopidogrel | 489/951 (51.4%) | 116 (51.1%) | 373 (53.5%) | 0.527 |
| Proton pump inhibitor | 270 (29.4%) | 70 (31.1%) | 200 (28.9%) | 0.528 |
| Coumarin derivates | 24 (2.5%) | 2 (0.9%) | 21 (3.0%) | 0.073 |
| Calcium channel blocker | 365 (39.8%) | 91 (40.4%) | 274 (39.6%) | 0.821 |
| Laboratory parameters | ||||
| Platelet count (× 10^9/L) | 273 ± 79 | 290 ± 78 | 268 ± 78 | <0.001 |
| White blood cell count (× 10^9/L) | 7.7 ± 2.6 | 7.9 ± 3.3 | 7.7 ± 2.3 | 0.359 |
| Haemoglobin (mmol/L) | 8.5 ± 1.0 | 7.9 ± 0.8 | 8.7 ± 0.9 | <0.001 |
| Procedural parameters | ||||
| Mean no. of stents implanted | 1.57 | 1.55 ± 0.9 | 1.57 ± 0.8 | 0.15 |
| Minimal stent diameter (mm) | 3.1 ± 0.8 | 3.1 ± 1.4 | 3.1 ± 0.6 | 0.67 |
| Total stent length (mm) | 28.3 ± 17.1 | 27.4 ± 17.2 | 28.6 ± 17.1 | 0.33 |
| Left anterior descending artery | 450/951 (47.3%) | 118/234 (50.4%) | 448/713 (46.3%) | 0.27 |
| Bifurcation lesion | 32/951 (3.4%) | 9/234 (3.8%) | 23/717 (3.2%) | 0.64 |
| Drug-eluting stent | 604/946 (63.8%) | 156/233 (67.0%) | 332/717 (62.8%) | 0.26 |
Definitions
Hypertension: Systolic blood pressure >140 mmHg or diastolic blood pressure >90 mmHg
Hypercholesterolaemia: A fasting LDL cholesterol ≥3.4 mmol/L or being on statin therapy at the time of inclusion
Diabetes mellitus: According to the World Health Organization criteria
Family history: One or more first-degree relatives have developed CAD before the age of 55 years (men) or 65 years (women)
Renal insufficiency: Serum creatinine >120 μmol/L