Table 1.

Age-adjusted characteristics of adenomatous and hyperplastic polyp cases and controls

Characteristic	Controls (N = 3431)	Adenomatous (N = 1529)	Hyperplastic (N = 499)	ρ-value*
Age (years, mean ± SD)	56.8 ± 7.7	58.8 ± 7.3	56.7 ± 7.0	<0.0001
Sex (female, %)	43.9	27.5	31.0	<0.0001
Race (%)
Caucasian	87.5	86.0	90.9	0.05
African American	10.5	11.7	8.0
Other	2.0	2.3	1.1
Smoking (%)
Current	12.7	28.3	33.8	<0.0001
Former	35.1	36.5	38.1
Never	52.2	35.2	28.1
Alcohol consumption (%)
Current	18.4	21.1	23.4	<0.0001
Former	22.4	29.3	27.4
Never	59.3	49.7	49.2
Family history of colon cancer or adenomatous polyp (yes, %)	14.6	16.6	14.7	0.17
Educational attainment (%)
High school or less	24.3	33.2	33.7	<0.0001
Some college	28.4	29.2	30.1
College graduate	20.7	19.8	18.6
Graduate or professional education	26.6	17.9	17.6
Regularly exercised (%)	57.8	49.8	54.4	<0.0001
Body mass index (kg/m2,mean ± SD)	28.1 ± 5.8	28.9 ± 5.7	28.8 ± 5.9	<0.0001
Use of HRT (ever, %)†	59.6	62.8	60.5	0.72
Study site (%)
Academic Center	72.7	58.8	55.5	<0.0001
VA	27.3	41.2	44.5
Indication for colonoscopy (%)
Screening	70.5	67.6	64.6	0.01
Diagnostic/bleeding/other	29.5	32.4	35.4

^*ANOVA for continuous variables and χ² test for categorical

^†Women only (n = 2082)