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Active site of rP4 inhibited by AMPS (relaxed stereographic view). AMPS is colored white; the S atom of AMPS is colored magenta. For reference, 5′-AMP from the D66N/5′-AMP structure (PDB code 3OCV) is also shown (yellow). Secondary structural elements of the core and cap domains are colored blue and pink, respectively. The yellow sphere represents Mg2+. The dashed lines denote electrostatic interactions in the AMPS complex.
