Figure 3.

Impaired corneal epithelial wound closure in DC-depleted mice. Corneal wounds were made by scraping the epithelia of CD11c-DTR mice s.c. injected with PBS (DTR+PBS) or DT (DTR+DT) or WT mice s.c. injected with DT (WT+DT). Wounded corneas were stained with 0.25% fluorescein sodium immediately after wounding (0 hpw) or at 24 hpw. A: Fluorescein staining of the original corneal epithelial wounds or at 24 hpw. The figure is representative of six corneas per condition from three independent experiments. B: The healing rate was expressed as the mean ± SD from five eyes each. *P < 0.05.