Table 1.
Differential miRNA Expression in Injury and Tolerance, Relative to Control
| miRNA | Injury | Tolerance | miRNA | Injury | Tolerance |
|---|---|---|---|---|---|
| miR10b | 8.54 | 1.0 | miR326 | 6.93 | −5.27 |
| miR21 | 44.58 | 21.66 | miR328 | 1.4 | 1.22 |
| miR-27a | 2.5 | −3.31 | miR330 | −3.89 | −7.69 |
| miR29a | 1.86 | 1.18 | miR374 | −2.76 | −10.1 |
| miR30e | 1.92 | 0.78 | miR375 | 12.31 | 1.10 |
| miR101 | 0.8 | −3.5 | miR381 | −4.76 | −6.58 |
| miR103 | 0.99 | −1.77 | miR422b | −4.33 | −2.70 |
| miR107 | 1.01 | −2.35 | miR425 | 2.16 | 1.05 |
| miR125a | 0.9 | 0.7 | miR451 | 3.44 | 4.33 |
| miR127 | 0.93 | −1.50 | miR487b | 1.46 | 1.15 |
| miR132 | 22.2 | 1.15 | miR497 | −2.35 | −3.67 |
| miR133b | −3.76 | −3.11 | miR507 | 76.91 | 1.0 |
| miR134 | 2.49 | 2.21 | miR509 | 7.89 | 13.93 |
| miR139 | 6.56 | 1.06 | miR518b | n.d | ND |
| miR145 | 1.15 | −1.61 | miR518c | n.d | ND |
| miR146b | 3.91 | 1.22 | miR518d | 143.92 | 70.40 |
| miR148b | 1.01 | −2.16 | miR520b | −52.63 | −39.21 |
| miR153 | 6.65 | 0.85 | miR520c | n.d | ND |
| miR181c | 1.01 | 0.90 | miR520g | n.d | ND |
| miR199a | 7.50 | 1.49 | miR532 | 1.47 | 0.83 |
| miR200a | 6.99 | −3.14 | miR629 | 1.0 | 2229 |
| miR219 | 22.96 | 5.16 | miR657 | −22.2 | −3.57 |
| miR323 | 22.62 | 1.38 |
The miRNA was extracted from the ipsilateral CA3 subfield 24 hours after focal-onset status epilepticus in animals that had previously received either seizure preconditioning (tolerance) or no preconditioning (injury). Values represent the fold difference relative to control for miRNAs expressed in injury and tolerance.
ND, not detected (expression in injury and tolerance was below the 35 cycle cutoff).