Figure 6.

Altered collagen fibrillogenesis in 952delTDcn transgenic mice. Fibrillogenesis is altered across the corneal stroma in the 952delTDcn transgenic mouse model. Note that in both the anterior and posterior stroma, collagen fibril diameter increases with the fibril distribution shifted to the right. The fibril distribution is heterogeneous in the mutant mice, and this feature is more pronounced in the posterior stroma. Scale bar = 200 nm; arrow indicates the position of the median in fibril diameter distribution.