Table 2.
LOX-1 ligands as determined by either direct binding assay or competitive assay (*) against established ligands
LOX-1 ligand | Molecule |
---|---|
Lipoproteins | oxidized LDL |
acetyl LDL | |
hypochlorite-modified HDL | |
remnant-like lipoprotein particle | |
electronegative LDL | |
carbamylated LDL | |
Proteins | CRP |
fibronectin | |
HSP60, HSP70 | |
Cells | activated platelets |
leukocytes/monocyte | |
aged/apoptotic cell | |
bacteria | |
Phospholipids | phosphatidylserine |
phosphatidylinositol* | |
phosphatidic acid* | |
cardiolipin* | |
phosphatidylglycerol* | |
Polyanions | heparin* |
dextran sulfate* | |
poly-inosinic acid* | |
Others | AGE |
2-nonenal/4-oxo-nonenal-bound protein |