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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Nutr Biochem. 2011 Jun 17;23(1):1–7. doi: 10.1016/j.jnutbio.2011.03.001

Figure 1. Role of ABCA1 in HDL formation.

Figure 1

Newly secreted apoA-I from the liver and small intestine interacts with ABCA1 and acquires phospholipids (PL) and free cholesterol (FC). The lipidation of apoA-I produce nascent HDL that subsequently undergoes maturation process by several factors including LCAT, CETP and PLTP to become spherical HDL.