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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Int Immunopharmacol. 2011 Jul 28;11(11):1809–1815. doi: 10.1016/j.intimp.2011.07.009

Fig. 1.

Fig. 1

Schedule of treatments. Animals were assessed for serum NicAb level starting at 1 week after the third vaccine dose. If serum NicAb levels were below the intended range after the third vaccine dose, a fourth dose was administered at day 63. When the serum NicAb level was within the intended range, the animal underwent 2 days of habituation, received the first dose of Nic311, and began nicotine dosing for the LMS protocol.