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. 2011 Nov;179(5):2327–2336. doi: 10.1016/j.ajpath.2011.08.001

Figure 5.

Figure 5

Quantification of IL-1β mRNA expression in the pancreas. IL-1β expression was examined by real-time PCR using RNA extracted from pancreatic tissue of WT, EBI3−/−, and WSX-1−/− mice treated with STZ in combination with recombinant IL-27 (rIL-27) or control vehicle on day 7. The mRNA expression levels were normalized with respect to glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression and expressed relative to that of WT mice treated with STZ alone. *P < 0.05 versus WT mice treated with STZ alone; **P < 0.05 versus EBI3−/− mice treated with STZ alone.