FIG. 4.
Effects of CTGF supplement on the gene expression of MSCs cultured on/in PGS-PCL scaffolds. (A) COL I; (B) ELA; (C) DEC; (D) HAS3; and (E) TIMP1. GAPDH was used as internal control and the relative gene expression was normalized to the baseline level at day 0 as indicated by the solid line. #Significant difference (p<0.05) relative to the baseline level at day 0; **significant difference (p<0.05) between the normal and the conditioned culture (A, C, E) or between day 7 and 21 normal culture (B). COL I, collagen type I; ELA, elastin; DEC, decorin; TIMP1, tissue inhibitor of metalloproteinases 1; HAS3, HA synthase 3.