Table 1.
Sample characteristics by alcohol exposure group (N = 25)
| Control (12) | Alcohol exposed (13) | t or χ2 | |
|---|---|---|---|
| Maternal characteristics | |||
| Age at delivery | 25.2 (3.4) | 26.5 (5.4) | -0.72 |
| Years of education | 8.4 (2.2) | 7.0 (2.7) | 1.44 |
| Married (%) | 38.5 | 50.0 | -0.56 |
| Parity | 2.6 (1.4) | 2.3 (1.1) | 0.54 |
| Alcohol during pregnancy | |||
| oz AA/day | 0.004 (0.01) | 2.7 (2.3) | -4.18*** |
| oz AA/occasion | 0.17 (0.4) | 6.5 (3.3) | -6.84*** |
| Frequency (days/week) | 0.03 (0.09) | 2.8 (1.4) | -7.24*** |
| Binges (frequency) | 0.08 (0.08) | 10.5 (5.8) | -6.46*** |
| Alcohol dependent (%)a | 11.1 | 76.9 | -9.21** |
| Cigarettes/day during pregnancy | 3.4 (3.4) | 8.6 (7.9) | -2.00† |
| Child characteristics | |||
| Child gender (% male) | 41.7 | 23.1 | -0.32 |
| Age at EBC visit | |||
| Delay conditioningb | 11.1 (1.2) | 11.1 (1.2) | 0.00 |
| Trace conditioningb | 12.7 (1.2) | 12.7 (1.3) | -0.04 |
| Years between delay and trace conditioningb | 1.5 (0.2) | 1.6 (0.1) | -0.36 |
| Age at DTI scan | 11.8 (1.2) | 11.8 (1.2) | 0.16 |
| Grade in school | 4.3 (1.3) | 3.7 (1.4) | 1.19 |
| Weight (kg)c | 34.2 (7.8) | 28.7 (7.2) | 1.82† |
| Height (cm)c | 136.5 (7.5) | 131.3 (9.6) | 1.49 |
| Head circumference (cm)c | 53.1 (1.5) | 51.1 (2.7) | 2.30* |
| WISC IQ | 76.6 (13.1) | 62.8 (9.3) | 3.05** |
| Volumetric measures (mm3)d | |||
| Total brain volume | 1.28 × 106 (1.52 × 105) | 1.14 × 106 (1.33 × 105) | 2.40* |
| Cerebellar volume | 1.49 × 105 (1.48 × 105) | 1.30 × 105 (1.94 × 105) | 2.60* |
| Cerebellar white matter | 3.21 × 104 (5.87 × 103) | 2.61 × 104 (4.73 × 103) | 2.74** |
| Cerebellar gray matter | 1.17 × 105 (1.05 × 104) | 1.04 × 105 (1.60 × 104) | 2.25 |
Values are means (SD).
Based on the NAWS; missing for three mothers.
N = 17 for whom both delay and trace data were available.
At dysmorphology assessment.
Missing for one child.
p < 0.10.
p < 0.05.
p < 0.01.
p < 0.001.