Table 2.
Substitution rates and times of most recent common ancestor (TMRCAs) of influenza A viral NP lineages*
| Lineage | Substitution rate (× 10−3) subs/site/year) |
TMRCA (calendar year) |
||||
|---|---|---|---|---|---|---|
| Mean | 95% HPD lower |
95% HPD upper |
Mean | 95% HPD lower |
95% HPD upper |
|
| A: Human | 1.98 | 1.69 | 2.27 | 1906 | 1884 | 1918 |
| B: Pandemic (H1N1) 2009 | 3.43 | 2.7 | 4.12 | 17-Dec-08 | 14-Jul-08 | 30-Mar-09 |
| C: Classical Swine | 2.29 | 1.99 | 2.58 | 1911 | 1888 | 1927 |
| D: Eurasian avian | 3.41 | 2.83 | 4.01 | 1920 | 1908 | 1927 |
| E: Eurasian swine | 2.8 | 2.4 | 3.21 | 1972 | 1963 | 1978 |
| F: North American avian | 2.25 | 1.95 | 2.53 | 1946 | 1932 | 1953 |
| H: Equine | 0.9 | 0.68 | 1.13 | 1947 | 1926 | 1959 |
Oceanian avian lineage (G): without enough sequences for reliable estimation of the parameters