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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Infect Genet Evol. 2011 Jul 7;11(8):2125–2132. doi: 10.1016/j.meegid.2011.07.002

Table 2.

Substitution rates and times of most recent common ancestor (TMRCAs) of influenza A viral NP lineages*

Lineage Substitution rate (× 10−3)
subs/site/year)
TMRCA (calendar year)
Mean 95% HPD
lower
95% HPD
upper
Mean 95% HPD
lower
95% HPD
upper
A: Human 1.98 1.69 2.27 1906 1884 1918
B: Pandemic (H1N1) 2009 3.43 2.7 4.12 17-Dec-08 14-Jul-08 30-Mar-09
C: Classical Swine 2.29 1.99 2.58 1911 1888 1927
D: Eurasian avian 3.41 2.83 4.01 1920 1908 1927
E: Eurasian swine 2.8 2.4 3.21 1972 1963 1978
F: North American avian 2.25 1.95 2.53 1946 1932 1953
H: Equine 0.9 0.68 1.13 1947 1926 1959
*

Oceanian avian lineage (G): without enough sequences for reliable estimation of the parameters