Table IV.
FPRP values for associations between risk of SCCHN and frequencies of rs8126 genotypes
| Genotype | Positive OR 95% CIa | Pb | Statistical powerc | Prior probability |
||||
| 0.25 | 0.1 | 0.01 | 0.001 | 0.0001 | ||||
| rs8126 T > C | TT versus CC/CT | |||||||
| All subjects | 1.26 (1.06–1.49) | 0.008 | 0.979 | 0.024 | 0.069 | 0.447 | 0.891 | 0.988 |
| Oropharynx | 1.26 (1.02–1.55) | 0.029 | 0.672 | 0.084 | 0.215 | 0.751 | 0.968 | 0.997 |
| Age > 57 years | 1.40 (1.09–1.79) | 0.008 | 0.713 | 0.033 | 0.092 | 0.526 | 0.918 | 0.991 |
| Alcohol ≤ 8.0 | 1.77 (1.28–2.45) | 0.001 | 0.204 | 0.014 | 0.042 | 0.327 | 0.830 | 0.980 |
The crude OR.
The omnibus chi-square test of the genotype frequency distributions.
Calculated using study subjects to detect an OR of 1.50 with the common genotype used as the reference.