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. Author manuscript; available in PMC: 2012 Sep 30.
Published in final edited form as: Circ Res. 2011 Aug 25;109(8):867–879. doi: 10.1161/CIRCRESAHA.110.236927

Figure 4.

Figure 4

Seven days after SU5416 administration, IR results in migration of TGFβ+ and IL-10+ expressing T cells into the lungs. (A) Immunofluorescent images of lung sections for Tregs cells (CD4+FoxP3+) (arrow) in athymic IR-SU group at d7 (n=7/group). (B) Immunofluorescent images of lung sections for CD4+IL-10+cells (arrow) in athymic IR-SU group at d7 (n=7/group). (C,D) Flow cytometry data of peripheral blood for FoxP3+and IL-10+ detection on d7 in athymic IR-SU group. (E) Immunofluorescent images of lung sections for CD4+TGFβ+ pSmad2/3+ cells (arrow) in athymic IR-SU group at d7 (n=7/group). (F,G,H,I) Western blot analysis from whole lung lysate and protein levels of pSmad2 and Smad2 on d7 and d21(n=8/group). Data are shown as means with error bars representing SEM. * p<0.05. Scale bar = 6.25 μm.