Effect of Ang II on insulin-induced glucose uptake. VSMCs were treated with 100 nmol/l Ang II or vehicle for 18 h in the presence or absence of an ARB, exposed to 10 nmol/l insulin for 30 min, and 2-deoxy-D-[3H]-glucose uptake measured. Data represent mean ± s.e. (n = 10) of percent change in uptake. *P < 0.05 vs. control. Ang II, angiotensin II; ARB, Ang II type 1 receptor blockers; VSMCs, vascular smooth muscle cells.