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. Author manuscript; available in PMC: 2012 Jan 27.
Published in final edited form as: J Med Chem. 2010 Dec 27;54(2):449–456. doi: 10.1021/jm100589p

Table 3. Inhibition of the proteolytic activities of proteasomes isolated from LCLs.

The IC50 values reported are the average of three independent determinations.

Isolated enzyme IC50(µM)
No CT-like T-like PGPH-like
2 4.8 6.6 6.2
3 4.2 8.4 >10
4 9.3 >10 >10