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HLH-associated gene mutations
| Gene | Location | Disease |
|---|---|---|
| PRF1 | 10q21-22 | FHL2 |
| UNC13D | 17q25 | FHL3 |
| STX11 | 6q24 | FHL4 |
| RAB27A | 15q21 | Griscelli syndrome |
| STXBP2 | 19p13 | FHL5 |
| Unknown | 9q21.3-22 | FHL1 |
| SH2D1A | Xq24-26 | XLP1 |
| XIAP | Xq25 | XLP2/X-linked HLH |
| LYST | 1q42.1-42.2 | Chediak-Higashi syndrome |
