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. 2011 Aug 15;118(15):4150–4158. doi: 10.1182/blood-2011-04-351072

Table 1.

Median time to treatment and OS relative to specific SET protein isoform expression

Time to treatment, y
OS, y
High expression Low expression P* High expression Low expression P*
SETβ-isoform 4.3 (3.7-6.2) 6.4 (4.5-9.3) .101 13.1 (11.3-NE) 16.9 (13.7-28.2) .229
SETα-isoform 3.8 (3.0-5.2) 8.3 (5.8-16.3) .0002 13.3 (11.3-22.6) 20.6 (14.5-NE) .247
Total SET (α + β) 4.3 (3.7-6.2) 11.9 (5.8-NE) .004 18.0 (12.3-28.3) 16.7 (12.7-NE) .997
α/β ratio 3.8 (3.1-5.2) 11.9 (6.3-NE) .0002 16.7 (10.6-22.6) 20.8 (15.8-NE) .008

Values are median (5th to 95th percentile).

NE indicates not estimable.

*

Determined by the proportional hazards method.