Table 1. Predominant virus genome composition upon in vitro selection of mixtures of pandemic (H1N1) 2009–seasonal (H1N1) and pandemic (H1N1)–seasonal (H3N2) influenza virus reassortants*.
| Replicates | PB2 | PB1 | PA | HA | NP | NA | M | NS |
|---|---|---|---|---|---|---|---|---|
| Pandemic (H1N1) 2009–seasonal (H1N1) 1 | sH1 | pH1 | sH1 | pH1 | pH1 | pH1 | pH1 | pH1 |
| Pandemic (H1N1) 2009–seasonal (H1N1) 2 | sH1 | pH1 | sH1 | pH1 | pH1 | pH1 | pH1 | pH1 |
| Pandemic (H1N1) 2009–seasonal (H1N1) 3 | sH1 | pH1 | pH1 | pH1 | pH1 | pH1 | pH1 | pH1 |
| Pandemic (H1N1) 2009–seasonal (H1N1) 4 | pH1 | pH1 | pH1 | pH1 | pH1 | pH1 | pH1 | pH1 |
| Pandemic (H1N1) 2009–seasonal (H3N2) 1 | pH1 | sH3 | pH1 | pH1 | pH1 | sH3 | pH1 | pH1 |
| Pandemic (H1N1) 2009–seasonal (H3N2) 2 | pH1 | pH1 | pH1 | pH1 | pH1 | sH3 | pH1 | pH1 |
| Pandemic (H1N1) 2009–seasonal (H3N2) 3 | pH1 | sH3 | pH1 | pH1 | pH1 | sH3 | pH1 | pH1 |
| Pandemic (H1N1) 2009–seasonal (H3N2) 4 | pH1 | sH3 | pH1 | pH1 | pH1 | sH3 | pH1 | pH1 |
*PB, basic polymerase; PA, acidic polymerase; HA, hemagglutinin; NP, nucleoprotein; NA, neuraminidase; M, matrix; NS, nonstructural; sH1, seasonal influenza A virus (H1N1); pH1, pandemic (H1N1) 2009 virus; sH3, seasonal influenza A (H3N2) virus.