Table 5.

Features of patients undergoing HDM/SCT and TRM during the first 10 years compared with the last 5 years

Feature	All (N = 421)	1994-2003 (N = 297)	2004-2008 (N = 124)	P
Age ≥ 65 y, %	17.3	17.2	17.7	.88
Creatinine > 2 mg/dL, %	17.1 N = 374	14.6 N = 260	22.8 N = 114	.05†
Time from diagnosis to SCT, months, median (range)	5.2 (1-143)	5.3 (1-143.5)	4.5 (1.6-107)	.03†
Cardiac involvement, %	45	41.4	54	.01†
Dominant cardiac involvement, %	16.8	17.2	16.1	.89
≥ 3 organs involved, %	43	43.7	41	.61
Full-dose melphalan, %	55	55.9	52.4	.51
BNP > 100 pg/mL,* %	54.3	—	54.3	—
TRM, %	11.4	13.8	5.6	.01

— indicates not applicable.

^*BNP test only available for 103 patients transplanted from 2004.

^†Statistically significant.