Skip to main content
. 2011 Aug 24;118(16):4366–4376. doi: 10.1182/blood-2011-04-350066

Table 1.

Summary of all highly purified HSC clones tested and average HSC expansion in vitro achieved in response to forced expression of NUP98-HOXA10hd

Phenotype tested CD45+linRhoSP E-SLAM
No. of NUP98-HOXA10hd HSC clones tested 28 17
No. of expanded HSC clones 25 15
Minimum cell dose (fraction of culture) transplanted 1/500 or 1/1000, or 1/2000 or 1/5000 1/500 or 1/1000
Average minimum HSC expansion in vitro estimated (LD not reached) > 806-fold > 942-fold
Range based on ± SEM 381 ± 1730 425 ± 2110
Average HSC expansion in vitro documented (LD reached) 2520-fold
Range based on ± SEM 1140 ± 5720

LD indicates limiting dilution.