Table 4. Comparison of levels of DNA adducts in livers of male mice treated with mixtures of carcinogenic PAHs between two diets (adducts in 109 nucleotides).
Time | Chemical | Dose | BPDE-dG Adduct | Total DNA adducts | ||||
CO | FO | P | CO | FO | P | |||
1 day | PAHs | High | 38.55 | 28.48 | 0.0008 | 80.49 | 52.35 | 0.0048 |
Low | 23.89 | 16.59 | 46.07 | 30.63 | ||||
3 day | PAHs | High | 40.48 | 25.56 | 72.58 | 44.99 | ||
Low | 20.90 | 12.73 | 31.25 | 21.76 | ||||
7 day | PAHs | High | 32.34 | 21.82 | 78.72 | 41.35 | ||
Low | 11.86 | 6.23 | 24.07 | 12.21 |