Table 5. Effects of dietary fish oil on hepatic gene expression of some metabolic enzymes.
Gene | Group | Normalized ΔΔ Ct values | P | |
CO (Mean±SEM) | FO (Mean±SEM) | |||
Cyp1a1* | DMSO | 5.38±0.36 | 5.28±0.13 | 0.903 |
HD PAHs | 2.69±0.07 | 6.32±0.31 | <0.001 | |
LD PAHs | 3.52±0.16 | 4.41±0.12 | 0.038 | |
Cyp1b1* | DMSO | 7.66±0.60 | 7.73±0.56 | 0.967 |
HD PAHs | 8.65±0.59 | 8.58±0.45 | 0.963 | |
LD PAHs | 8.19±0.54 | 9.88±0.46 | 0.232 | |
Gstt1** | DMSO | 8.20±1.19 | 18.38±3.63 | 0.037 |
HD PAHs | 21.03±2.60 | 27.05±1.69 | 0.100 | |
LD PAHs | 15.06±2.25 | 24.58±1.61 | 0.014 | |
Gstm1** | DMSO | 2.40±0.26 | 2.65±0.18 | 0.460 |
HD PAHs | 7.37±.11 | 8.24±0.61 | 0.517 | |
LD PAHs | 2.71±0.29 | 2.74±0.33 | 0.947 |
*2∧(−(Ct value − β-actin value − 15));
**2∧(−(Ct value − β-actin value − 3));
n = 4.