Table 3. Estimates of the rate ratios and the attributable fractions among men with different types of family history.
Type of clustering | RR (95% CI) | AFE (95% CI) | N |
1st degree relatives | |||
For all men | 2.48 (2.25–2.74) | 59.7% (55.6–63.5%) | 26 |
For men before the age of 65 | 2.87 (2.21–3.74) | 65.2% (57.7–71.4%) | 5 |
For men aged 65 or older | 1.92 (1.49–2.47) | 47.9% (37.1–56.8%) | 5 |
Affected father | 2.35 (2.02–2.72) | 57.4% (50.7–63.1%) | 18 |
Affected brother(s) | 3.14 (2.37–4.15) | 68.1% (58.1–75.7%) | 16 |
2+ 1st degree relatives | 4.39 (2.61–7.39) | 77.2% (65.4–85.0%) | 7 |
2nd degree relatives | 2.52 (0.99–6.46) | 60.4% (19.8–80.4%) | 5 |
RR: Rate Ratio, AFE: attributable fraction among those exposed, N: number of studies the estimates are based on.