Table 4.

Microscopic morphometry (intima and media layers) of aorta of rabbits treated with LDE-etoposide (6 mg/kg body weight/week) or saline solution (control group), for 8 weeks

	Control (n = 9)	LDE-etoposide (n = 9)
Total area (μm2) (×103)	0.40 ± 0.05	0.30 ± 0.02a
Media layer area (μm2) (×103)	0.30 ± 0.04	0.28 ± 0.01
Intima layer area (μm2) (×103)	0.10 ± 0.01	0.03 ± 0,01b
Intima/media area	0.30 ± 0.04	0.10 ± 0.03a

Notes: Data are expressed as mean ± SD.

^aP < 0.01;

^bP < 0.001 versus control.