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Expression of Bax, Bcl-2, and caspase 3 protein (A) and the Bax/Bcl-2 ratio (B) in the human SMMC-7721 hepatocarcinoma cells by Western blot after treatment with doxorubicin and/or TiO2 nanoparticles for 48 hours. Line 1, control; line 2, incubated with 10 μg/mL TiO2 nanoparticles; line 3, incubated with 0.5 μg/mL doxorubicin; line 4, incubated with 0.5 μg/mL doxorubicin and 10 μg/mL TiO2 nanoparticles.
Abbreviations: DOX, doxorubicin; TiO2, titanium dioxide; Nps, nanoparticles.
