Table 3.

Age of clinical events in SCID patients (n=39)^*

	Months (mean ± SD)
	diagnosis	treatment	death
SCID infants identified early+ (n=7)	1.0 ± 0	3.7 ± 4.3	all alive
SCID infants identified late− (n=32)	9.0 ± 7.6	9.6 ± 5.4	17.6 ± 10.4%
SCID infants with   HCT (n=23)	6.9 ± 5.0	9.8 ± 5.5	17.3 ± 7.5**
SCID infants with   no HCT (n=8)	15.4 ± 10.3		19.4 ± 14.0
SCID infant with PEG-   ADA therapy^ (n=1)	7	7	8

^*Based on survey responses from physicians and families of SCID children.

⁺Identified early is based on known family history of SCID, prior to manifestation of infections.

⁻Identified late is defined as confirmed with SCID after manifestation of infections.

^%Twenty out of 32 SCID patients identified late died.

^**Ten out of the 23 SCID patients transplanted died.

^$All eight SCID patients without HCT died.

^{^}PEG-ADA, polyethylene glycol-modified adenosine deaminase enzyme replacement, specifically for SCID with adenosine deaminase deficiency