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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Cell Signal. 2011 Sep 8;24(1):181–188. doi: 10.1016/j.cellsig.2011.08.021

Fig. 2. ILE86TER transgene rescues retinal degeneration. Retinal light micrographs.

Fig. 2

(A). An adult Pde6gtm1/Pde6gtm1 homozygote; (B). Pde6gtm1/Pde6gtm1 homozygote with the ILE86TER transgene; (C). ILE86TER/GCAPs−/− retina; and (D). C57B6 control. OS, outer segments; ONL, outer nuclear layer; INL, inner nuclear layer. The retina of the adult Pde6gtm1/Pde6gtm1 mouse lost all rod photoreceptors, and only a single layer of cones remains. Scale bars, 25 µm.