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MPs lack the MMP-inhibition activity found associated with the rest of microEC-secreted factors. (A) Samples of microEC MP and Sup fractions were analyzed via reverse zymography and by TIMP-1, TIMP-2, and TIMP-4 western blots. (B) Sup samples inhibited MMP-2, MMP-9, MMP-1, MMP-13, and MMP-14 activities more than Mem and MP samples. *** p< 0.001 Results are means ± SD.
